Omapatrilat or lisinopril in salt-sensitive hypertensives

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Omapatrilat versus lisinopril: efficacy and neurohormonal profile in salt-sensitive hypertensive patients.

Omapatrilat, a vasopeptidase inhibitor, simultaneously inhibits neutral endopeptidase and ACE. The efficacy and hormonal profile of omapatrilat and lisinopril were compared in salt-sensitive hypertensive patients. On enrollment, antihypertensive medications were withdrawn, and patients received a single-blind placebo. On day 15, salt-sensitivity determinations were made. Salt-sensitive hyperten...

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ژورنال

عنوان ژورنال: American Journal of Hypertension

سال: 2000

ISSN: 0895-7061

DOI: 10.1016/s0895-7061(00)00338-1